Endocrine Abstracts

Aims: Bening and malignant thyroid nodules are the most common lesions of endocrine glands. Some molecular markers; Mut-S homolog-2 (MSH2) and Mut-L-homolog-1 (MLH1) are the two of DNA repair proteins and metil guanin–DNA-metil transferase (MGMT) is the DNA repair enzymes have been studied. In this study, our aim is to evaluate MSH2, MLH1, and MGMT levels in papillary thyroid cancer (PTC), multinodular colloidal goitre (MNG), and chronic lymphocytic thyroiditis (CLT) and ...

Introduction: It was shown that a relationship between uric acid and cardiovascular diseases, and hyperuricemia is associated with systemic inflammation. But, determination of uric acid is widely available and inexpensive, it has been overlooked as a marker of systemic inflammation and metabolic disturbances. In this study, we aimed to evaluate uric acid value and its association with inflammation and metabolic disturbances in overweight and obese Turkish women.<p class="a...

Aim: Increased levels of fasting parathyroid hormone(PTH) have been hypothesized to influence increased levels of body fat mass. Preliminary studies show that serum PTH levels are higher in obese than in non-obese young adults and decline with weight loss. In the present study, it was aimed to evaluate relationship between antropometric and metabolic risk parameters and PTH levels in Turkish women.Materials and methods: Analyses were performed on 710 Tur...

Aim: Serum calcium levels have a relation glucose homeostasis and weight management, and controversies in findings. This study carried out relationship between serum calcium levels and various metabolic parameters in obese Turkish Women.Materials and methods: Subjects for this study were 3544 overweight or obese Turkish women with mean level of serum calcium 9.4 md/dl. According to mean calcium level, they divided group I having >9.4 mg/dl and group ...

Introduction: Serum ferritin concentration was found to be related with dyslipidemia, hypertension and abdominal adiposity. The aim of this study is to evaluate the correlations between serum ferritin concentrations and metabolic risk markers in obesity.Methods: Obese 534 women were enrolled into the study. The patients were divided into three tertiles according to the serum ferritin concentrations. The mean serum ferritin concentration was 9.96±4.1...

Introduction: The body fat distribution chances with menopause in women. The gluteo-femoral fat dominancy alters with central adiposity via menopause. The incidence of cardiovascular atherosclerosis increases with this period. Altered lipid profile and the increment in abdominal adipose tissue are suggested to be the influencing factors of this situation. The aim of this study was to evaluate the metabolic and anthropometric features of premenopausal and postmenopausal obese w...

Objective: The status of carbohydrate metabolism of pregnant women with positive glucose challenge test (GCT), but normal oral glucose tolerance test (OGTT); and their neonates have not defined clearly.Methods: Pregnant women with normal GCT (n: 120), with abnormal glucose challenge test (AGCT) but normal OGTT (n: 67) and those with gestational diabetes (GDM) (n: 67) were included into the study. Local ethical committee approval was ...

Introduction: Metabolic syndrome (MS) is a clustering of risk factors. Endothelial dysfunction has been reported in patients with MS and even in healthy obese individuals with a normal metabolic profile. Sympathetic activity commonly is increased in obese hypertensives, and moxonidine, is found to be effective in lowering blood pressure and improving insulin sensitivity. The aim of this study is to evaluate the efficacy of moxonidine on endothelial dysfunction in insulin-resis...

Objective: The measurement of epicardial adipose tissue (EAT) sonographically is reported to be related with both obesity and insulin resistance. Hepatic steatosis is one of the best known other coincidence with obesity. We aimed to evaluate the relationships between EAT thickness, hepatic steatosis and insulin resistance in obese patients.Methods: Obese 63 subjects were enrolled into the study. Local ethical committee approval was obtained. Patients wer...

Homeostasis of the body weight is maintaining by the interactions between the different sections of the brain and peripheral tissues. Diffusion weighted magnetic resonance imaging (DWI) is a method that investigates the microscopic motion of the water particules in tissues and also depends on measurement of the signal variations in tissues which is connected with the kinetic energy of the molecules called; molecular diffusion. The purpose of this work was to detect brain diffu...